Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- June 17, 2021

@caguayo Thanks for amplifying. We hope the article will initiate broad conversation about needed actions to diversify representation in research. Including @DarleenSandoval who led the effort and @GannonLab.
h J R
@msanderlab

- June 14, 2021

GTTs and ITTs are commonly used in metabolic research. Yet how the assays are designed and interpreted varies greatly between studies. This commentary provides an important resource to guide proper design and interpretation: https://t.co/z8ekyy98xA
h J R
@msanderlab

- June 7, 2021

@JeffreyRMillman Yeap. Same experience. I'd guess we requested some of the same lines.
h J R
@msanderlab

- June 3, 2021

Keep your eyes open for upcoming link for recorded sessions #Diabetes2021. Outstanding meeting and unique in that it married clinical and basic science perspectives. Thank you @NIH @NIDDKgov @CIHR_IRSC - let's bring together Canadian and US diabetes researchers more often! https://t.co/LCPAmvzGMs
h J R
@msanderlab

- June 3, 2021

@normrosenblum: 🌟 Fabulous speakers, moderators & engaging discussion at the Heterogeneity of Diabetes symposium today! ⏰ Join us at 9 am ET tomorrow for a Twitter Chat with @NIDDKgov using #Insulin100Chat followed by day 2 of the #Diabetes2021 symposium. ➡️https://t.co/niRqWV9oxD https://t.co/x8xYAMYy6O
h J R