Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

Congratulations to Wen and Nick on their new jobs!

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- February 14, 2019

#@UCSDMedSchool is recruiting in #diabetes research. Great #job opportunity for trainees or early career #faculty!… https://t.co/15w3gxbS9X
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@msanderlab

- February 14, 2019

Exciting new work from Herrera lab showing sustained reprogramming of human islet alpha cells into beta cells with… https://t.co/r6NRBbBj1N
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@msanderlab

- February 11, 2019

Saying goodbye to our postdoc Bjoern. Wishing you the best of luck in your new job! We will really miss you! https://t.co/IfACHsH8cU
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@msanderlab

- February 10, 2019

Congratulations to former Sander lab postdoc Janel Kopp, Assist. Prof. @UBC, for large @CIHR_IRSC research award f… https://t.co/wTCVYIJokF
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@msanderlab

- February 9, 2019

RT @millsjc67: The video recap of #KSPlasticity is now out in which Maike Sander @msanderlab , Ben Stanger and I summarize the state of the…
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