Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- December 5, 2021

Wonderful lab holiday party with Sander lab white elephant tradition. So nice to see everyone and their significant others. 😎⛱️☀️San Diego style! https://t.co/U7Bgn63bz8
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@msanderlab

- December 3, 2021

@CellPressNews: Stem cell based implants successfully secrete #insulin in patients with type 1 #diabetes. These phase I/II clinical trial data in @CellStemCell & @CellRepMed are the first evidence of meal-regulated insulin secretion by differentiated stem cells in human patients. Papers below!🧵 https://t.co/95RhFfFKj9
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@msanderlab

- December 2, 2021

Recruitment alert at UC San Diego! @UCSDMedSchool and @ucsdbe are jointly searching for Assistant Professor with research focus at interface of #bioengineering and #diabetes. Great research environment and city to live. Please RT broadly!! Apply at https://t.co/jgFCyEc3dT
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@msanderlab

- November 30, 2021

UC Irvine is looking for a new director of their Center for Epigenetics & Metabolism. https://t.co/XYIuS3apgA
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@msanderlab

- November 30, 2021

Congratulations to newly-minted Dr. Ryan Geusz 👏! Terrific defense - unfortunately by ZOOM - and incredibly productive graduate career. We can't wait to see what scientific endeavor will come next. https://t.co/Yk7NoVpBAG
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