Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- September 16, 2021

@SoleimanpourLab: 🚨🚨🚨Faculty recruitment alert! 🚨🚨🚨 We're recruiting new diabetes faculty at all levels in the @UMich Caswell Diabetes Institute. Please check out the link and get in touch or RT! Come join us in beautiful Ann Arbor! #GoBlue https://t.co/dDB26qeJ2g
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@msanderlab

- September 15, 2021

@HIRN_CC: Please join us once again in CONGRATULATING the 10 Scholarship Recipients from the 2021 HIRN Virtual Annual Investigator Meeting. These trainees submitted abstracts that were competitively reviewed by members of #HIRN & selected as being highly meritorious. #HIRN2021Scholarship https://t.co/e4rgXA23Dh
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@msanderlab

- September 15, 2021

@macara_ian: Our Cell and Developmental Biology faculty search at Vanderbilt has now gone live! Applications will be through Interfolio at the following link: https://t.co/62TWFBbNzh Ads will be posted online with Nature, Science and Cell.
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@msanderlab

- September 14, 2021

Congratulations to our postdoc Vy Nguyen-Ngoc for receiving a @HIRN_CC scholarship. Stay tuned for her talk at the upcoming HIRN Annual Meeting. https://t.co/BG1bZi10ed
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@msanderlab

- September 9, 2021

@UCSDMedSchool: Congrats to @msanderlab, @kjgaulton and team! With new $6.4M @genome_gov grant, they'll study how external signals and genetic variations influence insulin-producing beta cells in the pancreas—info that may enable better #diabetes prevention and treatment https://t.co/jrXSQSXZVo
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