Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

 

APPLY HERE

 

Congratulations to Wen and Nick on their new jobs!

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- October 12, 2018

RT @HIRN_CC: Please check the HIRN Website. We have listings of several open positions posted on our website for faculty, postdocs, and res…
h J R
@msanderlab

- October 7, 2018

We look forward to upcoming UCSD/IGM Genome and Transcriptome Engineering Conference on October 15! Awesome speaker… https://t.co/YqHGPwdqUA
h J R
@msanderlab

- September 28, 2018

Il cibo era delizioso! Saying goodbye to our postdoc Francesca. Best of luck in the next stage of your career! https://t.co/Gfvu87M1vD
h J R
@msanderlab

- September 28, 2018

The Program is out! Register now for the 2019 Gordon Research Conference on Pancreatic Diseases and explore links b… https://t.co/m7KJqq3HWO
h J R
@msanderlab

- September 27, 2018

Important study showing importance of native tissue architecture for correct cell behavior. Significant implication… https://t.co/KoiqtR0bon
h J R