Research in the Sander group is focused on understanding the molecular mechanisms that underlie the formation and function of insulin-producing beta cells in the pancreas, which are affected in diabetes. Our laboratory aims to identify strategies for beta cell regeneration and replacement in order to develop novel treatments for diabetes.

To understand cellular processes leading to diabetes, we employ genetic human pluripotent stem cell (hPSC)-based and mouse models. We interrogate these models with massively parallel sequencing and bioinformatic approaches and use functional assays to link molecular phenotypes to cell function and whole body physiology.

Our research is multi-disciplinary and highly collaborative. As part of the NIH-funded Human Islet Research Network (HIRN) we are generating a 3D islet organoid on a Chip and as part of the NIH-funded T2D-GENES Consortium we are using hPSC models to establish how genetic risk for diabetes causes cellular phenotypes.

We are looking for a postdoctoral researcher/senior scientist for integrative analysis of single cell data.

Dr. Maike Sander receives the Humboldt Research Award

@msanderlab

- January 26, 2023

@MDC_Berlin⁩ lunch break. Our own Russ Hogde performing. Art and science. Inspiration and creativity. https://t.co/bBX5jxJ8Mb
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@msanderlab

- January 24, 2023

Diabetes Germany reunion at FC Bayern game in Munich. ⁦@LickertHeiko⁩, Matthias Hebrok. ⁦@MatthiasTschop⁩ and Stephan Herzig with season tickets. https://t.co/XiGXRtWhtx
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@msanderlab

- December 8, 2022

Thank you @MDC_Berlin for this wonderful event. Thank you also to our guests who celebrated with us. https://t.co/SZ2cDhVrvx
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@msanderlab

- December 1, 2022

Congratulations 👏🏻👏🏻to Han for a well-deserved award. Here, you can read more about his recent work: https://t.co/vEE0v3y3Fi https://t.co/NIE8RbcmSj
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